The International High Speed Intelligent Communication (HSIC) is an important field of theory, design, and implementation of millimeter wave integrated circuits and systems, sensor network, optical communications and MIMO/OFDM systems. Previous three HSIC were held by Chang Gung University (2009), Nanyang Technology University (2010) and City University of Hong Kong (2011), respectively. The HSIC2012, jointly organized by Southeast University, and Chang Gung University, will be held in Nanjing on 10-11 May 2012. The theme of the HSIC2012 is “Technologies for Next Generation Wireless Communications” to promote more high speed chip designs and the development of intelligent circuits/systems techniques to enhance the smart system command and control capability and to display the highly intelligent communication performances. The HSIC2012 will offer a rich program of high quality with distinguished invited speakers from all over the world and provide a broad forum of exchanges for researchers and scholars.